Mannose drying

Mannose drying is a critical downstream process that converts purified D-mannose (a C-2 epimer of glucose) into stable, free-flowing powders or crystals for pharmaceutical, nutraceutical, and food applications. Common drying method: Hot boiling drying

Mannose drying is a critical downstream process that converts purified D-mannose (a C-2 epimer of glucose) into stable, free-flowing powders or crystals for pharmaceutical, nutraceutical, and food applications. This dehydration step ensures product stability, precise dosing, and functional performance in end-use formulations like urinary health supplements and IV therapies.

Purpose & Importance
Stabilization:

Reduces moisture to ≤0.5% w/w to prevent:

Maillard reactions (browning)

Microbial growth

Hydrolysis-induced degradation

Functionality Enhancement:

Improves flowability for direct compression (tablets/capsules).

Maintains rapid solubility (>90% in 20°C water).

Polymorph Control:

Preserves α/β crystalline ratios critical for dissolution kinetics.

Common drying method

Hot boiling drying
The granular solid material is added to the fluidized bed dryer by the feeder, the filtered clean air is heated and sent to the bottom of the fluidized bed by the blower, and contacts the solid material through the distribution plate, to form fluidization to achieve air-solid heat and mass exchange. After the material is dried, it is discharged from the discharge port, and the exhaust gas is discharged from the top of the fluidized bed, and the solid powder is recovered by the cyclone dust collector and bag dust collector before being emptied.